Question 489 · LEK · Anaphylaxis

A 38-year-old female was administered intravenous ciprofloxacin infusion due to acute pyelonephritis. Shortly after the infusion start, the patient complained of heat sensation and scratchy throat. Physical examination revealed stridor, blood pressure of 70/58 mmHg and then below detection limits. Aside from withholding the infusion, first of all the patient should be administered:

  1. A. adrenaline (epinephrine) 0.5 mg intramuscularly;.
  2. B. adrenaline (epinephrine) 0.5 mg intravenously;.
  3. C. 500 mL 0,9% NaCl intravenous bolus;.
  4. D. clemastine 1.0 mg intravenously;.
  5. E. hydrocortisone 100 mg intravenously.
Hint

Identify the first-line drug in anaphylaxis and the route that is both effective and safe outside a monitored cardiac arrest setting.

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