Question 494 · LEK · Acromegaly

A 58-year-old female, during diagnostics for abnormal blood glucose levels, reported noticing a substantial increase in her shoe size. Upon further questioning she admitted that her family noticed a change in her facial features. In this case we need to determine the level of:

  1. A. insulin-like growth factor type 1.
  2. B. β₂-microglobulin.
  3. C. anti-myeloperoxidase antibodies.
  4. D. transforming growth factor beta.
  5. E. free testosterone.
Hint

Larger feet and coarser facial features with abnormal glucose suggest excess of a pituitary hormone; screen with its stable peripheral mediator.

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