Question 479 · LEK · Esophageal cancer

Indicate the true statement regarding esophageal adenocarcinoma (EAC):

  1. A. EAC more often affects pre-menopausal women.
  2. B. The main risk factor for EAC is alcohol consumption.
  3. C. EAC is not associated with tobacco use.
  4. D. The risk of EAC is nearly 30 times greater in people with achalasia.
  5. E. Intestinal metaplasia of the lower esophagus is a precancerous condition.
Hint

Think of the reflux-induced change in the distal oesophageal epithelium that precedes this type of cancer.

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