Question 342 · LEK · Acute kidney injury

A 79-year-old woman with acute kidney injury, oliguria and with severe muscle pain was admitted to the hospital. Which of the drugs taken by this patient should be immediately withdrawn?

1) lisinopril 40 mg/day;
2) simvastatin 40 mg/day;
3) metoprolol 50 mg/day;
4) amlodipine 10 mg/day;
5) telmisartan 80 mg/day.
The correct answer is:
  1. A. 1,2,3.
  2. B. 1,2,4.
  3. C. 1,2,5.
  4. D. 1,3,4.
  5. E. 1,3,5.
Hint

Muscle pain with oliguric AKI suggests drug-induced rhabdomyolysis; also consider which drugs lower glomerular filtration pressure.

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