Question 329 · LEK · Multiple myeloma

Which of the following is the most characteristic abnormality in patients with multiple myeloma?

  1. A. generalized lymphadenopathy.
  2. B. hepatomegaly.
  3. C. splenomegaly.
  4. D. osteolytic bone lesions.
  5. E. plasmacytic infiltration in the kidneys.
Hint

Think about what clonal plasma cells do to bone by activating osteoclasts.

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