Question 266 · LEK · Cardiovascular risk and prevention of cardiovascular diseases

A 54-year-old woman treated with atorvastatin (40 mg daily) for hyperlipidemia for several years came for a control examination. She takes ramipril 10 mg because of arterial hypertension. She is not diabetic, her history is positive for TIA (transient ischemic attack). The examination shows: BMI 27.8 kg/m², RR 138/76 mmHg. Lab tests: total cholesterol 6.62 mmol/L (255 mg%), LDL-cholesterol 4.34 mmol/L (166 mg%), HDL-cholesterol 0.9 mmol/L (35 mg%), triglycerides 1.8 mmol/L (160 mg%), ALT in the normal range. Indicate the optimal management of her lipid disorders:

  1. A. addition of fibrates.
  2. B. addition of ezetimibe.
  3. C. addition of ion-exchange resins.
  4. D. addition of nicotinic acid.
  5. E. continuation of the pharmacological treatment, dietary counseling, body mass reduction.
Hint

Define her cardiovascular risk category after TIA, compare LDL-C with the target and pick the logical add-on to a statin.

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