Question 271 · LEK · Dysphagia

A 34-year-old patient complains of nausea and pressure-like sensation behind the sternum, especially after solid meals. The symptoms occur intermittently for 3 years, mainly in summer and autumn. He underwent the standard treatment for gastroesophageal reflux disease but without any improvement. He was diagnosed with asthma in the childhood. The gastroscopy revealed no macroscopic lesions and biopsy of the esophageal mucosa was performed. Which of the following is the most probable cause of the symptoms?

  1. A. esophagitis in the course of gastroesophageal reflux disease.
  2. B. esophageal cancer.
  3. C. eosinophilic esophagitis.
  4. D. esophageal achalasia.
  5. E. diffuse esophageal spasm.
Hint

Note the young age, atopy, seasonal pattern, failure of reflux therapy and a normal-looking oesophagus that still needed biopsies.

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