Question 196 · LEK · Chronic kidney disease

The clinical symptoms of chronic (end-stage) renal failure indicating the necessity to start renal replacement therapy (dialysis) do not include:

  1. A. lack of appetite, nausea and possible development of malnutrition.
  2. B. significant fluid retention with dyspnoea and crepitations at the bases of both lungs despite loop diuretics being used chronically in high dose.
  3. C. systolic blood pressure > 200 mmHg despite high doses of antihypertensive drugs from 5 groups (beta-blocker, alpha-blocker, calcium channel blocker, loop diuretic and clonidine).
  4. D. gout.
  5. E. pruritus not responding to hydroxyzine.
Hint

Which of these is a uremic complication that dialysis relieves, and which is a common metabolic problem managed with drugs?

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