Question 195 · LEK · Treatment of hypertension with comorbidities

Indicate the false statement concerning the use of loop diuretics in patients with arterial hypertension and chronic kidney disease:

  1. A. loop diuretics are effective even in patients with glomerular filtration rate (GFR) < 15 ml/min/1,73 m2.
  2. B. use of large doses of loop diuretics may lead to dehydration and a decrease of GFR.
  3. C. loop diuretics should not be used in patients without hyperkaliemia.
  4. D. use of diuretics combined with angiotensin-converting-enzyme inhibitors decreases albuminuria.
  5. E. use of large doses of loop diuretics may lead to hearing impairment.
Hint

Loop diuretics are chosen in CKD because they still work at low GFR — is hyperkalemia a prerequisite for using them?

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