Question 169 · LEK · Clostridioides difficile infection and pseudomembranous colitis
Indicate the true statement on the treatment of first episode of mild pseudomembranous colitis:
- A. first choice treatment is metronidazole and/or vancomycin, administered i.v.
- B. first choice treatment is metronidazole or vancomycin, administered orally.
- C. treatment should be started from pulses of vancomycin (10 times every third day, for 27 days).
- D. treatment should always include the proton pump inhibitor.
- E. first choice medicament is clindamycin.
Hint
Consider where C. difficile and its toxins are located and which route of administration actually delivers the drug to the colonic lumen.
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