Question 171 · LEK · Kidney cysts
Which of the following concerning autosomal dominant polycystic kidney disease (ADPKD) is true?
1) ADPKD is the commonest genetically determined kidney disease;
2) liver cysts are often a non-renal manifestation of ADPKD;
3) in the course of ADPKD, significantly more often than in general population, clear cell renal cell carcinoma develops;
4) vasopressin V2 receptor antagonist turned out to be effective in delaying cyst enlargement;
5) calcium channel blockers are first choice drugs in the treatment of arterial hypertension.
The correct answer is:
2) liver cysts are often a non-renal manifestation of ADPKD;
3) in the course of ADPKD, significantly more often than in general population, clear cell renal cell carcinoma develops;
4) vasopressin V2 receptor antagonist turned out to be effective in delaying cyst enlargement;
5) calcium channel blockers are first choice drugs in the treatment of arterial hypertension.
The correct answer is:
- A. 1,2,3,4.
- B. 1,2,4,5.
- C. 2,3,4.
- D. 1,2,4.
- E. all the above.
Hint
Recall the extrarenal features of ADPKD, the drug that slows cyst growth, and which antihypertensive class targets the activated RAAS.
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