Question 148 · LEK · Glomerular diseases
Antibodies taking part in the primary pathogenesis of membranous nephropathy are antibodies:
- A. against the non-collagen domain of the α3 chain (collagen IV) of glomeruli.
- B. against the podocyte membrane phospholipase A2 receptor (PLA2R).
- C. anti-C1q.
- D. against proteinase 3.
- E. against myeloperoxidase.
Hint
In most primary cases the target antigen sits on the podocyte surface.
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