Question 64 · LEK · Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Indicate the false statement concerning syndrome of inappropriate antidiuretic hormone secretion - SIADH:

  1. A. diagnosis of SIADH is not possible without the exclusion of adrenal insufficiency.
  2. B. risk of central pontine myelinolysis increases with too a rapid correction of hyponatremia.
  3. C. urine sodium determination is diagnostically significant only if the patient does not take diuretics.
  4. D. correction of hyponatremia requires the administration of a concentrated (3%) saline solution in the majority of patients.
  5. E. serum osmolarity is lower than 280 mOsm/kg, while urine osmolarity should be above 100 mOsm/kg.
Hint

Most SIADH patients are only mildly symptomatic; think about what first-line correction of their hyponatremia involves.

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