Question 345 · LEK · Infectious mononucleosis
Differential diagnosis of Epstein-Barr virus (EBV) infection relies on specific antibodies. Select the correct antibody test result in a patient with past infection (the patient had the infection previously):
1) anti-VCA IgM - positive result;
2) anti-VCA IgM - negative result;
3) anti-VCA IgG - positive result;
4) anti-VCA IgG - negative result;
5) anti-EA IgG - positive result;
6) anti-EA IgG - negative result;
7) anti-EBNA - positive result;
8) anti-EBNA - negative result.
The correct answer is:
2) anti-VCA IgM - negative result;
3) anti-VCA IgG - positive result;
4) anti-VCA IgG - negative result;
5) anti-EA IgG - positive result;
6) anti-EA IgG - negative result;
7) anti-EBNA - positive result;
8) anti-EBNA - negative result.
The correct answer is:
- A. 1,3,5,6.
- B. 2,4,6,8.
- C. 2,3,6,7.
- D. 1,4,6,8.
- E. 2,4,5,8.
Hint
IgM reflects acute infection, while EBNA antibodies appear only weeks to months after the acute phase and persist for life.
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