Question 315 · LEK · Celiac disease

Indicate the true statements concering celiac disease:

1) Dühring’s disease is its variant.
2) not adhering to the gluten-free diet increases the risk of development of lymphomas in celiac disease patients.
3) detecting the presence of HLA DQ2 and HLA DQ8 constitutes a 100% confirmation of the diagnosis.
4) the first symptom in a child can be slowing down of the somatic development.
5) there may be a secondary occurrence of lactase deficiency.
The correct answer is:
  1. A. 1,2,3.
  2. B. 1,2,4,5.
  3. C. 2,3,4.
  4. D. 3,4,5.
  5. E. all the above.
Hint

Remember that HLA typing has a high negative but low positive predictive value, and think of extra-intestinal and long-term consequences.

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