KROK 1 2010 – Question 105 · KROK (Medicine) · Pharmacology

A 66 year old female patient got intravenous injection of magnesium sulfate solution for the purpose of elimination of hypertensive crisis. But arterial pressure didn’t go down and after repeated introduction of the same preparation there appeared sluggishness, slow response, inhibition of consciousness and respiration. What preparation is antagonist of magnesium sulfate and can eliminate symptoms of its overdose?

  1. A. Calcium chloride
  2. B. Potassium permanganate
  3. C. Activated carbon
  4. D. Potassium chloride
  5. E. Sodium chloride
Hint

Think about the physiological antagonist that competes with this cation at presynaptic terminals and restores the release of transmitter, thereby reversing central and respiratory depression.

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