KROK 1 2010 – Question 92 · KROK (Medicine) · Pathophysiology
A 62 year old patient who previously worked as stoker was admitted to a hospital with complaints about general weakness, abrupt weight loss, hoarse voice, dyspnea, dry cough. Laryngoscopy revealed a tumour in the pharynx that invaded vocal cords and epiglottis. What is the most probable cause of tumour development?
- A. Retroviruses
- B. Aromatic amines and amides
- C. Nitrosamines
- D. Ionizing radiation
- E. Polycyclic aromatic hydrocarbons
Hint
Think about what a stoker inhales for years from burning coal, and which class of chemical carcinogens in that smoke acts on the epithelium of the upper airways.
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