KROK 1 2009 – Question 35 · KROK (Medicine) · Pathophysiology

A female patient suffering from bronchial asthma had got a viral infection that provoked status asthmaticus with fatal outcome. Histological examination of lungs revealed spasm and edema of bronchioles, apparent infiltration of their walls with lymphocytes, eosinophils and other leukocytes; labrocyte degranulation. What mechanism of hypersensitivity underlies the described alterations?

  1. A. Autoimmune
  2. B. Immune cytolysis
  3. C. Immune complex
  4. D. Inflammatory
  5. E. Reagin reaction
Hint

Focus on what triggers the degranulation of mast cells and why eosinophils gather in the bronchiolar wall.

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