KROK 1 2009 – Question 15 · KROK (Medicine) · Pharmacology
A patient suffering from stomach ulcer has been treated with an antacid drug almagel. For acute bronchitis treatment he was prescribed the antibiotic methacycline. However within next 5 days the fever didn’t fall, cough and sputum nature remained unchanged. A physician came to the conclusion that the drugs were incompatible. What type of drug incompatibility is the case?
- A. Pharmacodynamic
- B. Pharmacokinetic, absorption stage
- C. Pharmaceutic
- D. Direct antagonism
- E. Pharmacokinetic, biotransformation stage
Hint
Ask what the aluminium and magnesium in the antacid can do to the antibiotic while both are in the gut, and which phase of drug handling that affects.
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