KROK 1 2019 – Question 67 · KROK (Medicine) · Biology

The mother’s karyotype has 45 chromosomes. It was determined that translocation of chromosome 21 to chromosome 14 had occurred. What disorder is likely to be observed in the child of this woman if the father’s karyotype is normal?

  1. A. Edwards syndrome
  2. B. Down syndrome
  3. C. Patau syndrome
  4. D. Klinefelter syndrome
  5. E. Morris syndrome (androgen insensitivity)
Hint

Work out how many copies of chromosome 21 material the child receives when the carrier mother's gamete with the fused chromosome meets a normal sperm.

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