KROK 1 2018 – Question 181 · KROK (Medicine) · Physiology

Vascular endothelium is characterized by high metabolic activity and synthesizes vasoactive substances. Among these substances there is a potent vasodilator synthesized from L-arginine. Name this vasodilator:

  1. A. Nitrogen oxide
  2. B. Histamine
  3. C. Adrenaline
  4. D. Acetylcholine
  5. E. Bradykinin
Hint

Consider what the endothelial enzyme that uses L-arginine as its substrate produces, and how that product reaches the underlying smooth muscle to relax it.

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