KROK 1 2017 – Question 137 · KROK (Medicine) · Biology

Cystinuria manifests itself in a human as cystine stones in the kidneys (homozygous individuals) or increased cystine content in the urine (heterozygous individuals). Cystinuria is a monogenic disorder. Determine the type of interaction between the genes of cystinuria and normal urine cystine excretion:

  1. A. Codominance
  2. B. Semidominance
  3. C. Epistasis
  4. D. Complete dominance
  5. E. Complementarity
Hint

Compare the phenotype of the heterozygote with those of both homozygotes and ask whether it matches either one or lies in between.

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