Question 219 · LEK · Lymphomas and other systemic tumors

A maculopapular skin rash, cradle cap not responding to the treatment, swelling of the gums and abnormal teething, soft on palpation bulges of the skull, and X-ray revealing osteolytic lesions in bones of the cranial vault in a 1-year-old child are characteristic of:

  1. A. vitamin D-resistant rickets.
  2. B. Fanconi syndrome.
  3. C. pseudohypoparathyroidism.
  4. D. hypothyroidism.
  5. E. Langerhans cell histiocytosis.
Hint

A seborrheic-like rash plus lytic skull lesions and gum involvement in an infant suggests a clonal disorder of dendritic cells.

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