Question 94 (part 2) · LEK · Serological incompatibility, alloimmunization and hemolytic disease of the fetus and newborn

Which of the following is true about the prevention of serological conflict connected with the administration of anti-D immunoglobulin:

  1. A. the aim of the immunoprophylaxis is the neutralization of the maternal antigens which have entered the foetal circulation.
  2. B. the prevention is instituted within 24h after ectopic pregnancy, invasive surgery in pregnancy and episodes of mid-pregnancy bleeding.
  3. C. the prevention can be instituted on condition that anti-D antibodies are present in the serum of an Rh-negative patient.
  4. D. the prevention can be instituted on condition that there is no D antigen in the red blood cells of the newborn.
  5. E. the immunoprophylaxis is a safety measure only for one pregnancy (the next one).
Hint

Consider how long passively administered anti-D antibodies persist and whether they create lasting immunity.

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