Question 15 (part 2) · LEK · Gestational trophoblastic disease
Which genetic abnormality is characteristic of trophoblastic disease and differentiates complete hydatidiform from partial hydatidiform?
- A. chromosome 15 aneuploidy.
- B. chromosome 17 short arm deletion.
- C. diploidy and the presence of only paternal chromosomes.
- D. trisomy 21.
- E. pentasomy X.
Hint
Think about the number and parental origin of chromosome sets in each mole: an empty ovum versus dispermic fertilisation of a normal ovum.
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