Question 1 (part 2) · LEK · Urinary system

Which is true about serum uric acid in pregnant women in a normal, uncomplicated pregnancy?

  1. A. it keeps increasing with the quickest rise observed in the second part of the pregnancy.
  2. B. it keeps decreasing since the beginning of pregnancy and reaches the lowest level in 22 nd-24th week of pregnancy. Then it starts increasing until the due date to reach the pre-pregnancy level.
  3. C. it remains unchanged in the first trimester of pregnancy, after which it increases until the due date.
  4. D. it remains unchanged.
  5. E. it increases until 24th week of pregnancy when it reaches a plateau and stays the same until the due date.
Hint

Think about how the rise in renal plasma flow and GFR in early pregnancy affects uric acid clearance, and what happens closer to term.

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