Question 87 · LEK · Protozoal infections

A 25-year-old woman in 12th week of her first pregnancy made a test of antibodies against Toxoplasma gondii. The results were as follows: IgG = 300 IU/mL, IgM (-). A similar test performed 2 years earlier showed: IgG = 480 IU/mL, IgM (-). The patient should be informed that:

  1. A. there is a high risk of an infection with Toxoplasma gondii caused by the consumption of both raw meat and contaminated fruit and vegetables.
  2. B. she has to repeat the test of antibodies against T. gondii every 6-8 weeks during the whole pregnancy.
  3. C. she should undergo antiprotozoal treatment.
  4. D. she was infected with Toxoplasma gondii before the pregnancy (most probably it was a subclinical infection) and her child is not at risk of the infection.
  5. E. it is necessary to perform invasive diagnostics for the infection (amniocentesis, examination of the amniotic fluid for protozoan cysts).
Hint

Interpret a positive IgG with negative IgM that was already present two years before conception.

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