Question 18 (part 2) · LEK · Treatment
The blood pressure of a 54-year-old patient could not be lowered to the desired level although three drugs i.e. perindopril, indapamide and amlodipine had been used. The patient’s eGFR is 64 ml/min/1.73 m2, and potassium concentration is 4.1 mmol/l. Which of the following drugs should be considered the first one to use in order to reduce the patient’s blood pressure?
- A. methyldopa.
- B. verapamil.
- C. doxazosin.
- D. spironolactone.
- E. losartan.
Hint
Resistant hypertension on an ACE inhibitor, a calcium channel blocker and a diuretic: which fourth drug has the best evidence if potassium and eGFR allow?
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