Question 504 · LEK · Nephrotic and nephritic syndromes
In a 82-year-old female with history of rheumatoid arthritis diagnosed at the age of 20 years, severe peripheral pitting oedema appeared. Due to proteinuria found in a spot urine sample, 24-hour urine collection was ordered, which revealed proteinuria of 32 grams per day. In this situation you should suspect:
- A. IgA nephropathy.
- B. amyloidosis.
- C. acute tubulointerstitial nephritis.
- D. minimal change disease.
- E. lupus nephropathy.
Hint
Decades of chronic inflammation can lead to kidney deposits of a protein derived from an acute-phase reactant.
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