Question 463 · LEK · Primary sclerosing cholangitis

A 23-year-old female patient with a history of ulcerative colitis for the past few months has had pruritus and sporadic right-sided subcostal pain. In the previous month she had an episode of jaundice with a fever up to 38°C. Ultrasound examination performed at that time did not show cholecystitis and the patient was disqualified from surgery. Considering the patient’s history, the suspected diagnosis is:

  1. A. primary sclerosing cholangitis.
  2. B. cytomegalovirus infection.
  3. C. acute hepatitis E.
  4. D. lymphoma confined to the liver.
  5. E. Gilbert syndrome.
Hint

Link the patient's inflammatory bowel disease with cholestatic features such as pruritus, jaundice and febrile episodes suggesting cholangitis.

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