Question 390 · LEK · Chronic myeloid leukemia
Chronic myeloid leukemia is characterised by:
- A. high leukocytosis due to eosinophilia, enlarged spleen, enlarged lymph nodes.
- B. lymphocytosis, enlarged spleen and lymph nodes.
- C. leukocytosis (increased WBC) with blasts, immature forms of neutrophils and neutrocytes (“blood smear like bone-marrow smear”), enlarged spleen.
- D. pancytopenia, enlarged lymph nodes.
- E. pancytopenia, enlarged spleen.
Hint
Think of a myeloproliferative neoplasm with the Philadelphia chromosome: what does the peripheral smear look like and which organ enlarges?
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