Question 328 · LEK · Granulomatosis with polyangiitis

What is the most probable disease presented with fever, cutaneous purpura, purulent rhinorrhea, nasal ulcers, sinus pain, polyarthralgia/arthritis, cough, hemoptysis, shortness of breath, microscopic hematuria and mild proteinuria?

  1. A. membranous nephropathy.
  2. B. antiglomerular basement membrane disease.
  3. C. granulomatosis with polyangiitis (Wager’s granulomatosis).
  4. D. poststreptococcal glomerulonephritis.
  5. E. IgA nephropathy.
Hint

Combine necrotizing upper airway inflammation, lung involvement and glomerulonephritis.

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