Question 292 · LEK · Hyperparathyroidism

A 77-year-old patient treated for urolithiasis for many years complains of a generalized bone pain. Laboratory tests show: calcium concentration 12.3 mg/dL (N: 8.5-10.5 mg/ dL), daily calcium excretion 480 mg/24h (N: 150-300 mg/24h), PTH 227 pg/ml (N: 15-65 pg/mL). The most probable diagnosis is:

  1. A. hypercalcemia of malignancy.
  2. B. primary hyperparathyroidism.
  3. C. secondary hyperparathyroidism.
  4. D. pseudohypoparathyroidism.
  5. E. vitamin D overdose.
Hint

Read calcium and PTH together: is PTH appropriately suppressed or inappropriately high for this calcium level?

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