Question 218 · LEK · Acute liver failure
The first-choice drug used in treatment of acute liver failure related to paracetamol (acetaminophen) overdose is:
- A. N-acetylcysteine.
- B. BAL.
- C. vitamin E (high doses).
- D. glutathione.
- E. barbiturate.
Hint
The antidote works by replenishing hepatic glutathione, which detoxifies the toxic paracetamol metabolite NAPQI.
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