Question 129 · LEK · Microscopic colitis
A 68-year-old patient for several weeks has complained of abdominal cramps, watery diarrhoea with the bowel movements 4-8 daily and bloating. Since then she has lost 4 kg. Periodically she has suffered from lumbar backache and takes diclofenac together with PPI as a gastroprotection. Routine laboratory tests were within normal limits. Ileocolonoscopy did not show any abnormalities. Biopsies taken during colonoscopy from the right half of the colon revealed lymphocyte and plasmocyte infiltration in lamina propria of the colon mucosa. The most probable diagnosis of the patient’s complaints is:
- A. microscopic colitis.
- B. exudative enteropathy.
- C. small intestine bacterial overgrowth (SIBO).
- D. Whipple’s disease.
- E. hyperthyroidism.
Hint
Chronic watery diarrhea, a normal-looking colonoscopy, NSAID plus PPI use and inflammation visible only under the microscope.
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