Question 98 · LEK · Anemia of chronic disease

The main laboratory features of the anemia of chronic diseases are:

  1. A. decreased serum iron, increased transferrin level, decreased transferrin saturation, decreased ferritin.
  2. B. elevated serum iron level, elevated transferrin saturation, decreased ferritin.
  3. C. decreased serum iron level, decreased or normal transferrin level, decreased transferrin saturation, normal or increased ferritin level.
  4. D. red blood cell macrocytosis, decreased serum iron level, elevated transferrin level, decreased ferritin level.
  5. E. red cell normo- or microcytosis, decreased iron level, elevated transferrin saturation, increased ferritin level.
Hint

In inflammation hepcidin traps iron in macrophages: stores are preserved while serum iron is low; apply this to ferritin and transferrin.

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