Question 45 · LEK · Anticoagulants
Numerous interactions between vitamin K antagonists (VKA) and other medications or food must be considered in patients chronically treated with VKA. Which of the following intensify the action of VKA?
1) carbamazepine;
2) ciprofloxacin;
3) amiodarone;
4) spinach;
5) grapefruit juice;
6) mesalazine.
The correct answer is:
2) ciprofloxacin;
3) amiodarone;
4) spinach;
5) grapefruit juice;
6) mesalazine.
The correct answer is:
- A. 1,2,3,6.
- B. 1,4,6.
- C. 2,3,4.
- D. 1,3,5,6.
- E. 2,3,5.
Hint
Separate CYP inhibitors from enzyme inducers, and remember which food supplies vitamin K and therefore opposes VKA.
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