Question 271 · LEK · Oncogenetics

92 z 117 29.06.2026, 14:15 Centrum Egzaminów Medycznych https://test.cem.edu.pl/pytcem/wyswietl_baza_pdf.php Which of the statements below is false in relation to hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome)?

  1. A. it occurs early in life with the average age of diagnosis between 40 and 50.
  2. B. it is more common in men.
  3. C. it is more commonly located on the right side of the colon.
  4. D. it occurs more commonly as two tumours in the colon detected simultaneously (synchronous cancer).
  5. E. its typical feature is the occurrence of subsequent tumours in the part of the colon that was not excised during surgery (metachronous cancer).
Hint

Recall the classic features of Lynch syndrome: age at onset, preferred colonic site, multiplicity of tumours and mode of inheritance.

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