Question 113 · LEK · Oncogenetics
Indicate the true statements concerning Lynch syndrome (hereditary nonpolyposis colorectal cancer):
1) it is an autosomal dominantly inherited disease;
2) one of its variants is Gardner’s syndrome;
3) diagnosis is based on the Amsterdam criteria;
4) age of onset is usually between 20-30 years of life;
5) adrenal cancer is more common.
The correct answer is:
2) one of its variants is Gardner’s syndrome;
3) diagnosis is based on the Amsterdam criteria;
4) age of onset is usually between 20-30 years of life;
5) adrenal cancer is more common.
The correct answer is:
- A. 1,3.
- B. 2,3.
- C. 2,4,5. 39 z 117 29.06.2026, 14:15 Centrum Egzaminów Medycznych https://test.cem.edu.pl/pytcem/wyswietl_baza_pdf.php
- D. only 1.
- E. only 3.
Hint
Lynch syndrome is a mismatch repair gene disorder; recall its inheritance, clinical criteria, age of onset and extracolonic cancers.
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