Question 250 · LEK · Introduction
Which of the following statements are true for immunization in children with impaired immunity?
1) live vaccines, such as MMR, are contraindicated in children with severe immunodeficiency;
2) children with HIV should avoid all live vaccines regardless of their immunosuppression level;
3) influenza vaccine (inactivated) is indicated in children with immunodeficiency also during immunosuppression;
4) prematurely born children should receive pneumococcal vaccination using a 3-dose primary vaccination schedule followed by 1 booster dose;
5) varicella vaccination can be safely administered in children using oral prednisone 25 mg/day.
The correct answer is:
2) children with HIV should avoid all live vaccines regardless of their immunosuppression level;
3) influenza vaccine (inactivated) is indicated in children with immunodeficiency also during immunosuppression;
4) prematurely born children should receive pneumococcal vaccination using a 3-dose primary vaccination schedule followed by 1 booster dose;
5) varicella vaccination can be safely administered in children using oral prednisone 25 mg/day.
The correct answer is:
- A. 1, 2, 3.
- B. 1, 3, 4.
- C. 1, 4, 5.
- D. 2, 3, 5.
- E. 2, 4, 5.
Hint
Live vaccines are contraindicated only with significant immunosuppression; recall the corticosteroid dose threshold and how CD4 levels affect HIV vaccination.
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