Question 11 (part 2) · LEK · Somatic diseases and psychiatry

A 50-year-old woman who has been treated for depression with sertraline for almost two years complains of weakness, cold intolerance, constipation and weight gain, all of which have been present for about 6 months. Physical examination revealed dry, rough skin, bradycardia, hypothermia and hand and foot oedema. Which of the following tests will the most useful in establishing the diagnosis:

  1. A. liver function tests.
  2. B. a serum electrolytes test.
  3. C. measurement of oestrogen levels in the serum.
  4. D. measurement of sertraline levels in the serum.
  5. E. measurement of thyrotropic hormone levels in the serum.
Hint

Fatigue, cold intolerance, constipation, weight gain, dry skin and bradycardia form a classic endocrine pattern — which hormone screens for it?

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