Question 113 · LEK · Antidepressants

A 56-year-old patient visited the psychiatrist because of apathy, anhedonia, hopelessness, and decreased appetite for about 2 months. The patient has not been treated psychiatrically but she is treated for hypertension. The psychiatrist’s initial diagnosis is “moderate depressive episode”. Which of the following medications should he prescribe?

  1. A. alprazolam - small doses 3 times a day regularly, with the additional dose in the case of elevated blood pressure.
  2. B. olanzapine - small doses, which will improve appetite in the initial phase of treatment.
  3. C. escitalopram - SSRI medication, used in depression treatment.
  4. D. venlafaxine - SNRI medication, used in depression treatment.
  5. E. combined therapy A and D.
Hint

Choose a first-line antidepressant, keeping in mind which option could worsen her hypertension.

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