Question 101 · LEK · Antipsychotics

A 33-year-old patient came to her family doctor. She has been treated psychiatrically for bipolar disease and has been taking olanzapine (10 mg daily) for two months. She has not been diagnosed with any other chronic disease. The patient complains of the weight gain of 5 kg (weight: 82 kg, height: 175 cm, BMI: 26.8 kg/m²). What is the minimal set of laboratory tests recommended for monitoring the treatment with olanzapine?

1) TSH, fT3, fT4;
2) creatinine;
3) glycemia;
4) bilirubin;
5) electrolytes;
6) creatine phosphokinase;
7) lipid profile.
The correct answer is:
  1. A. 1,5.
  2. B. 2,5.
  3. C. 2,6.
  4. D. 3,7.
  5. E. 4,6.
Hint

Olanzapine carries one of the highest risks of metabolic syndrome; choose the tests that reflect this risk.

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