Question 21 · LEK · Antidepressants

Persistent pain is one of the symptoms accompanying depression that can significantly worsen its course. Which of the following antidepressants should be considered in such a clinical setting?

1) duloxetine;
2) trazodone;
3) agomelatine;
4) venlafaxine;
5) milnacipran.
The correct answer is:
  1. A. only 2.
  2. B. only 4.
  3. C. 3,5.
  4. D. 1,2,4.
  5. E. 1,4,5.
Hint

Think of the antidepressants that block reuptake of both serotonin and noradrenaline, strengthening descending pain inhibition.

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