Question 364 · LEK · Bone tumors

Indicate true statement regarding the treatment of osteosarcoma in children:

  1. A. preoperative chemotherapy includes ifosfamide, cisplatin, adriamycin, and high-dose methotrexate with calcium folinate.
  2. B. surgery is performed before the start of chemotherapy to prevent tumour dissemination.
  3. C. limb amputation is the treatment of choice.
  4. D. treatment is carried out in paediatric rheumatology centres as part of the solid tumour programme.
  5. E. prognosis does not depend on the stage of the disease or the response to treatment.
Hint

Modern osteosarcoma treatment is multimodal; think about the order of chemotherapy and surgery.

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