Question 230 · LDEK · Local anesthetics
The impaired effect of local anesthetics in an inflamed tissue is caused by:
- A. clogging up the potassium channels of the phospholipid neuronal cell membrane.
- B. inactivation of the sodium-potassium pump.
- C. excessive accumulation of sodium ions inside the neuronal cell.
- D. escape of potassium ions from the neuronal cell to the extracellular space.
- E. reduced pH of the environment.
Hint
Think about the acid-base chemistry of local anaesthetics and which form crosses the nerve membrane.
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