Question 35 · LDEK · Pharmacotherapy in oral surgery

Indicate the true statements concerning Hoigne syndrome:

1) it is a complication of the intravenous administration of procaine penicillin;
2) it manifests with blood pressure elevation, bradycardia and hyperventilation that are followed by vomiting and marked pupil dilation;
3) symptoms subside spontaneously after 30 to 60 minutes or after steroid administration;
4) Hoigne symptom in medical history is a contraindication to penicillin administration.
The correct answer is:
  1. A. 1,2.
  2. B. 1,2,4.
  3. C. only 2.
  4. D. only 1.
  5. E. 1,2,3.
Hint

Hoigné syndrome is a non-allergic toxic-embolic reaction; think about heart rate, how it resolves and what that means for future penicillin use.

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