Question 44 (part 2) · LDEK · Host response

Inflammatory mediators which inhibit osteoclasts’ function include:

1) IL-1;
2) IL-6;
3) IL-10;
4) TGF-β 1;
5) TNF;
6) RANKL;
7) PGE2;
8) OPG.
Correct answer is:
  1. A. 1,2,3,4,5.
  2. B. 1,2,5,6,7.
  3. C. 3,4,8.
  4. D. 3,5,7,8.
  5. E. 4,5,6,7,8.
Hint

Separate the pro-resorptive cytokines and RANKL from the anti-inflammatory cytokines and the decoy receptor that neutralises RANKL.

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