Question 220 · LDEK · Dental plaque and calculus
Which hypothesis concerning the bacterial pathogenesis of periodontal disease called for a shift from eubiotic to dysbiotic microbiome due to periopathogens capable of dysregulating certain elements of inflammation and immune response?
- A. the specific plaque hypothesis.
- B. the opportunistic infection hypothesis.
- C. the ecological plaque hypothesis.
- D. the key pathogen hypothesis.
- E. the Inflammation-Mediated Polymicrobial Emergence and Dysbiotic Exacerbation (IMPEDE) model.
Hint
Which hypothesis says that a low-abundance pathogen such as P. gingivalis subverts host immunity and thereby remodels the whole community?
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