Question 71 (part 2) · LDEK · Children with systemic diseases and disabilities

Proliferative-oedematous lesions appeared in the area of mandibular molars in a 12-year-old female, 5 years post kidney transplantation. Histopathology and immunohistochemical assay confirmed post-transplant lymphoproliferative disorder. Indicate the virus associated with this disease’s etiology:

  1. A. Epstein-Barr virus.
  2. B. measles.
  3. C. chickenpox (varicella).
  4. D. HHV-8.
  5. E. HPV-16.
Hint

Recall which oncogenic virus is classically linked to B-cell proliferation in immunosuppressed transplant recipients, especially seronegative children.

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